Readings

Many of the readings come from the course textbook, "Brock": Madigan, Michael, and John Martinko. Brock Biology of Microorganisms. 11th ed. Upper Saddle River, NJ: Pearson Prentice Hall, 2006. ISBN: 0131443291.


LEC # TOPICS LECTURERS READINGS
1 Early Earth/Microbial Evolution Prof. Ed DeLong Chapter 11 in Brock
2 Cell Structure/Function Prof. Ed DeLong Chapter 4 in Brock
3 Biological Energy Conservation Prof. Ed DeLong Chapters 5 and 17 in Brock
4 Microbial Growth Prof. David Schauer Chapter 6 in Brock
5 Metabolic Regulation Prof. Ed DeLong
6 Virology Prof. David Schauer Chapter 9 in Brock
7 Information Flow in Biological Systems Prof. Ed DeLong Chapter 10 in Brock
Midterm I
8 Regulation of Cell Activity Prof. Ed DeLong Chapter 8 in Brock
9 Genetic Exchange in Bacteria Prof. Ed DeLong
10 Experimental Evolution: Optimization of Metabolic Systems Guest Lecturer, Prof. Christopher Marx from Harvard Marx, Christopher J., Stephen J. Van Dien, and Mary E. Lidstrom. "Flux Analysis Uncovers Key Role of Functional Redundancy in Formaldehyde Metabolism." PLOS Biology 3 (2005): 244-253. (PDF)
11 Genomics I Prof. Ed DeLong Chapter 15 in Brock
12 Genomics II Prof. Ed DeLong Chapter 15 in Brock
13 Metabolic Diversity I Prof. Ed DeLong Chapter 17 in Brock
14 Metabolic Diversity II Prof. Ed DeLong Chapter 17 in Brock
15 Microbial Ecology Prof. Ed DeLong Chapter 19 in Brock
Midterm II
16 Microbial Growth Control Prof. David Schauer Chapter 20 in Brock
17 Microbe-host Interactions Prof. David Schauer

Chapter 21 in Brock

Backhed, Fredrik, et al. "Host-Bacterial Mutualism in the Human Intestine." Science 307 (2005): 1915-1920.

18 Immunology I Megan McBee Chapters 22 and 23 in Brock
19 Immunology II Megan McBee
20 Diagnostic Microbiology Prof. David Schauer Chapters 21 and 24 in Brock
21 Person-to-person Transmission Prof. David Schauer Chapter 25 in Brock
22 Epidemiology Megan McBee Chapter 26 in Brock
23 Animal- and Arthropod-transmitted Diseases Prof. David Schauer Chapter 27 in Brock
24 Review Prof. David Schauer Chapters 28 and 29 in Brock
Final Exam

Other Readings

Backhed, Fredrik, et al. "Host-Bacterial Mutualism in the Human Intestine." Science 307 (2005): 1915-1920.

Berg, Howard. "Motile Behavior of Bacteria." Physics Today on the Web (January 2000).

Galan, Jorge E., and Hans Wolf-Watz. "Protein Delivery into Eukaryotic Cells by Type III Secretion Machines." Nature 444 (2006): 567-573.

Jetten, Mike S. M., et al. "Microbiology and Application of the Anaerobic Ammonium Oxidation (‘Anammox’) Process." Environmental Biotechnology 12 (2001): 283-288.

Lovley, Derek R. "Bug Juice: Harvesting Electricity with Microorganisms." Nature Reviews Microbiology 4 (2006): 497-508.

Marx, Christopher J., Stephen J. Van Dien, and Mary E. Lidstrom. "Flux Analysis Uncovers Key Role of Functional Redundancy in Formaldehyde Metabolism." PLOS Biology 3 (2005): 244-253. (PDF)

Moran, Nancy A., Fordon R. Plague, Jonas P. Sandstro, and Jennifer L. Wilcox. "A Genomic Perspective on Nutrient Provisioning by Bacterial Symbionts of Insects." PNAS 100 (2003): 14543-14548.

Nakabachi, Atsushi, et al. "The 160-Kilobase Genome of the Bacterial Endosymbiont Carsonella." Science 314 (2006): 267.

Pace, Norman R. "Time for a Change." Nature 441 (2006): 289.

Purcell, E. M. "Life at Low Reynolds Number." American Journal of Physics 45 (1977): 3-11.

Santiago, F. Elena, and Richard E. Lenski. "Evolution Experiments with Microorganisms: The Dynamics and Genetic Bases of Adaptation." Nature Reviews Genetics 4 (2003): 457-469.

Tamas, Ivica, et al. "50 Million Years of Genomic Stasis in Endosymbiotic Bacteria." Science 296 (2002): 2376-2379.

Wu, Dongying, et al. "Metabolic Complementarity and Genomics of the Dual Bacterial Symbiosis of Sharpshooters." PLOS Biology 4 (2006): 1079-1092. (PDF - 1.0 MB)